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Coat Colour E-locus – e1 (red/yellow) H734

69,00 €

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General information

Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Extension, or E-Locus, corresponds to the gene ‘melanocortin 1 receptor’ (MC1R), which is involved in the regulation of pigment production. Mutations affecting the E-locus often result in a lightening of the coat, from black or brown to red, yellow or even white.
This E-locus variant, designated as e^1, is a recessive mutation primarily observed in the Golden Retriever, Irish Setter and Labrador Retriever. Related variants are known to occur in the Husky and Australian Cattle Dog.

Clinical features

Affected dogs (e/e) typically have a fully red to yellow coat. Depending on the breed, this may be designated as apricot, cream, white, etc.

Additional information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.

References

Pubmed ID: 10602988

Omia ID: 1199