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Coat Color Sabino 1 P785

56,87 €

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Background

During the last decades, a large number of scientific publications have described the genetic principles of coat colour and coat variation. Coat colours and coat variations are influenced by many hereditary factors. The DNA-tests are based on physiological effects in the body, in which the production and distribution of pigments result in many coat colour variants. In several cases, the coat colour of an animal may only be decided using DNA-tests. Sabino is a general description for a group of similar white spotting patterns. The sabino pattern is described as irregular spotting usually on the legs, belly and face, often with roaning around the edges of the white markings. A mutation has been discovered that produces one type of sabino pattern, it has been named Sabino1 as it is not present in all sabino-patterned horses. More mutations will probably exist that account for other sabino patterns. The Coat Colour Sabino 1 test (P785) tests for the genetic status of the KIT gene. This gene has two variants (alleles). The allele SB1 is semi-dominant. One copy of the SB1 allele results in horses with broken Sabino markings and possibly only a small amount of white. Two copies of the SB1 allele result in at least 90% white, also referred to as Sabino-white. The allele N is recessive and does not have an effect on the basic colour.

Test specific information

This test is also included in a Combination Package Coat Colour. Since 2015, two brands have been developed. CombiGen? is mainly directed at veterinarian applications, whereas CombiBreed? is mainly directed at breeders and/or owners.Detailed information about Coat Colours and Coat Variation is presented at www.pharmaDNA.com.

Age

Most coat colours and coat types are usually visible directly after birth.

Throughput

Normally the result can be expected within 15 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.

Location of disease or trait

Genetic factors influencing coat colours and coat types are usually visible on the outside of an individual. Several factors may be hidden by the external variation.

Breed dependence

For this test samples from all breeds are accepted.

Sample type

For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact PharmaDNA if you wish to submit other material as listed.

Result

Coat colours are based on many genetic factors. For each factor, a separate test result will be returned.

Inheritance

Various genetic factors influencing coat colour and coat types are inherited in a dominant or recessive mode. Coat colours are influenced by a large number of genetic factors.

Severity of Disease

Genetic characteristics are not a disease.