Background
Parentage verification is based on the comparison of genetic information from Offspring, Dam and Sire. The basis of parentage verification can be used in many species, including animals, birds, fish and humans. Sample material such as hair roots, swabs, semen and several other materials can be used for parentage verification. Of each sample, a DNA-profile is established using DNA-markers. The DNA-profile from each sample is stored in a database, and can be presented as barcode. A barcode is unique for an individual. The process of parentage verification involves a comparison of the genetic information present in an offspring with the DNA present in the possible parents. For a correct parentage, all genetic information in an Offspring must be present in the combination of Dam and Sire. In most parentage verifications, the reliability of the analysis is at least 99,5 percent. In addition to parentage verification, a DNA-profile can be used to verify the identity of an individual. The reliability of such analysis is extremely large, because all genetic information in two samples must be identical.
Test specific information
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Age
Parentage analysis based on DNA can be done at any moment in life. A DNA-profile does not change during life. The assessment of a DNA-profile can be done using virtually every material that includes cellular and nuclear material.
Throughput
Normally the result can be expected within 15 working days. This turn-around-time starts when both the sample and the fully filled-out and signed submission form have been received.
Location of disease or trait
Parentage verification based on DNA can in principle be performed using any material that contains cells with a nucleus.
Breed dependence
For this test samples from all breeds are accepted.
Sample type
For this DNA test we accept the following materials: Hair, Semen, Blood EDTA, Blood Heparin, Tissue. Please contact PharmaDNA if you wish to submit other material as listed.
Result
The result of a parentage verification or control of identity is restricted to the questions asked. In routine cases, the conclusion is based on a large number of DNA-markers. This results in a quality of more than 99 percent if both parents are present. The reliability of a parentage verification is reduced if parents are missing or need to be reconstructed. Also, the quality of the test is influenced by the genetic variation within a population.
Inheritance
In parentage verification DNA-markers are visualized, in which a DNA-marker has two genetic variants. One genetic variant is paternal in origin, whereas the other genetic variant is maternal. It is possible to assess if any genetic variant is present in an offspring that is not detected in a parent. Visualizing sufficient DNA-markers will provide a good reliability to parentage verification.
Severity of Disease
Parentage verification, kinship analysis and/or control of identity are no disease.
